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M94A2535.TXT
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Document 2535
DOCN M94A2535
TI HIV incidence in a cohort of Burundian male workers.
DT 9412
AU Tobi S; Buzingo T; Sokal D; Kamuragiye A; Rubayiza E; Alexandre Y;
Family Health International, Burundi.
SO Int Conf AIDS. 1994 Aug 7-12;10(1):282 (abstract no. PC0048). Unique
Identifier : AIDSLINE ICA10/94370040
AB OBJECTIVE: To study longitudinally the epidemiology of new HIV-1
infection in a cohort of workers in the capital city, to provide
information for policy makers about the scope and direction of the AIDS
epidemic in Burundi. METHODS: Between 1990 and 1993, 2,430 workers from
five companies in Bujumbura were enrolled into the cohort. New
volunteers were encouraged to participate each year. Men who were HIV-1
negative at the time of recruitment were retested yearly to determine
the annual incidence rate of new infection. A KAP survey was
administered at the time of testing to provide information about risk
factors for infection. HIV testing was by Elisa with confirmation by
Western Blot. RESULTS: More than 50% of the workers volunteered for the
study. Among those who volunteered, Sixty-one percent of seronegative
men were followed in 1991, 76% in 1992, and 77% in 1993. Prevalence
among new volunteers was 14.3% in 1990, 13.8% in 1991, 13.0% in 1992,
and 10.6% in 1993 (chi 2 test for trend = 2.19, p = .14). The 1990/1991
incidence rate was 2.1/100 person-years. In 1991/1992 it was 2.1/100
person-years, and in 1992/1993 it was 2.5/100 person-years. Risk factors
for seroconversion included occurrence of urethritis (IRR = 2.8, 95% CI
= 1.2-6.4), reported occurrence of genital ulcer (IRR = 4.2, 95% CI
1.9-9.5), and having more than one sexual partner (IRR = 1.93, 95% CI =
1.1-3.3) during the risk period (i.e., since last seronegative test).
CONCLUSIONS: To the extent that newly recruited workers represent the
general populations of workers, there is an apparent leveling off of HIV
prevalence. Despite this observed trend, the incidence rate of HIV-1
continues to be high. Although observed prevalence may result form
participation bias, this finding reinforces the need to exercise caution
in interpretation of prevalence data.
DE Burundi/EPIDEMIOLOGY Cohort Studies Human HIV
Infections/*EPIDEMIOLOGY *HIV-1 Knowledge, Attitudes, Practice Male
Prevalence Risk Factors MEETING ABSTRACT
SOURCE: National Library of Medicine. NOTICE: This material may be
protected by Copyright Law (Title 17, U.S.Code).